Conference Agenda

20th September 2021. Day 1.

Opening Ceremony

Reading from the Qur’an

Dynamics of function and regulation of the endoplasmic reticulum

Keynote Speaker:
Prof Kazutoshi Mori, Lasker laureate
(Kyoto University, Japan)

Qatar Diabetes Prevention Program (QDPP) – use of A1C in diabetes prevention and control

Prof Abdul-Badi Abou-Samra
(Metabolic Research Institute, Hamad Medical Corp, Qatar)

Transactivation of the Receptor for Advanced Glycation Endproducts mediating proinflammatory signaling in diabetes

Prof Mark Cooper
(Monash University, Australia)

Challenging the Dogma in Diabetic Neuropathy

Prof Rayaz Malik
(Weill-Cornell Medical College, Qatar)

RAGE/DIAPH1: Molecular Mechanisms and Therapeutic Strategies in Obesity and Diabetic Complications

Prof Ann Marie Schmidt
(New York University, USA)

Targeting the gut to reduce AGE-mediated damage in diabetes

Associate Prof Melinda Coughlan (Monash University, Australia)

Pre-session on-line poster discussion session 1 (Posters 1 – 22)

Glycation and development of healthier foods

Prof Vincenzo Fogliano (University of Wageningen, The Netherlands)

Manuka honey and its unique glycation chemistry

Prof Thomas Henle (Technical University of Dresden, Germany)

Does the quote “Sola dosis facit venenum” apply to the physiological effects of glycation adducts?

Prof Fred Tessier
(University of Lille, France)

Immunogenicity and allergenicity of glycated cows’ milk proteins

Dr Gosia Teodorowicz
(University of Wageningen, The Netherlands)

Structure of melanoidins formed in the Maillard reaction of methylglyoxal with L-alanine or L-lysine

Dr Clemens Kanzler
(Technische Universität Berlin, Germany)

Fluidized bed roasting drives Maillard reactions toward A more aromatic cocoa

Ruth Fabiola Peña-Correa
(University of Wageningen, The Netherlands)

Methylglyoxal stress in obesity and (risk of) type 2 diabetes

Prof Casper G. Schalkwijk (Maastricht University,
The Netherlands)

Dicarbonyl stress in insulin resistance and effect of exercise intervention

Prof Jacob Haus
(University of Michigan, USA)

Dicarbonyl stress in diabetic vascular disease

Prof Bernd Stratmann
(Ruhr-University Bochum, Germany)

Higher habitual intake of dietary dicarbonyls is associated with higher concentrations of corresponding plasma dicarbonyls and with skin autofluorescence: the Maastricht Study

Dr Kim Maasen
(Maastricht University, The Netherlands)

Dynamics of hexokinase-2 linked glycolytic overload driving dicarbonyl stress and endothelial cell dysfunction in high glucose concentration in vitro

Prof Naila Rabbani
(Qatar University, Qatar)

Pyridoxamine reduces glycation and markers of endothelial function in a placebo-controlled intervention trial with abdominally obese individuals

Dr Mathias Van den Eynde
(Maastricht University, The Netherlands)

Virtual Trade Exhibition (Exhibitors available on-line for inquiries and discussion)

Pre-session on-line poster discussion session 2 (Posters 23 – 44)

RAGE and maternal bonding – an unexpected mechanistic relationship

Prof Yasuhiko Yamamoto
(Kanazawa University, Japan)

Ascorbic acid as a glycating agent in the aging lens

Prof Vincent Monnier (Case Western Reserve University, USA)

Glyoxalase 1 activity declines with age in many tissues

Prof Allen Taylor
(Tufts University, USA)

Short term intraperitoneal administration of mammalian cell derived human soluble receptor for advanced glycation end products (sRAGE) prevents type 1 diabetes onset in mice

Selena Le Bagge
(University of Queensland, Australia)

High hydrostatic pressure processing of human milk avoids the formation of Maillard reaction products and preserves oligosaccharides

Dr Michael Howsam
(University of Lille, France)

Effect of a 4-week diet low and high in AGEs on insulin sensitivity and secretion, vascular function, and markers of low-grade inflammation and endothelial dysfunction of abdominally obese individuals – preliminary results from the deAGEing trial

Armand Linkens
(Maastricht University, The Netherlands)

Production mechanism of methylglyoxal and its reactivity with oxygen to produce reactive oxygen species in illuminated chloroplasts of plant leaves

Prof Chikahiro Miyake (Kobe University, Japan)

Glycation of plant proteins – a step forward to understanding the biological role

Prof Andrej Frolov
(St. Petersburg State University, Russia & Leibnitz Institute of Plant Biochemistry, Halle, Germany)

Glyoxalases: the antidote for methylglyoxal and plant stress

Prof Sneh L. Singla‐Pareek
(International Centre for Genetic Engineering and Biotechnology, India)

Drought-related changes in pea root nodule metabolome

Dr Alena Soboleva
(St. Petersburg State University, Russia & Leibnitz Institute of Plant Biochemistry, Halle, Germany

Evaluation of MG antiviral activity against SARS-CoV-2

Mrs Israa Elbashir
(Qatar University, Qatar)

Anti-inflammatory activity of glyoxalase-1 inducer, trans-resveratrol and hesperetin, in human small airway epithelial cell primary cultures support application for prevention of COVID-19.

Prof Paul J Thornalley
(QBRI/HBKU, Qatar)

Virtual Trade Exhibition (Exhibitors available on-line for inquiries and discussion)

Pre-session on-line poster discussion session 3 (Posters 45 – 67)

Detection of reactive carbonyl intermediates of glycation

Prof Monika Pischetsrieder (University of Erlangen-Nuremberg, Germany)

Measurement of AGEs: LC-MS/MS, immunoassay and finger skin autofluorescence

Prof Ryoji Nagai
(Tokai University, Japan)

Mechanochemistry: Maillard Reaction “Through the Looking Glass”

Prof Varoujan Yaylayan (McGill University, Canada)

Update to the N6-carboxymethyl lysine story

Prof Marcus Glomb
(Martin-Luther University of Halle, Germany)

Enzymatic decarboxylation of Nε-carboxymethyl-lysine by ornithine decarboxylases reveals underground metabolism as a route for in vivo processing of glycated amino acids

Prof Michael Hellwig
(Technical University Braunschweig & Technical University Desden, Germany)

Polyphenols as trapping agents of reactive carbonyl species: new strategy to reduce harmful compounds in e-cigarette emissions

Dr Alberto Fiore
(University of Abertay, United Kingdom)

Organelle stress and metabolic derangement in kidney disease

Prof Reiko Inagi (University of Tokyo, Japan)

Methylglyoxal metabolism is a targetable liability of glycolytic metabolism in cancer

Prof Matthew Vander Heiden (MIT, USA)

Glycation and mental health – anxiety, depression and schizophrenia

Prof Makoto Arai (University of Tokyo, Japan)

Multiple Outcome Studies Confirm Predictive Value of AGEs for Diabetic Kidney Disease

Prof Paul J Beisswenger
(Dartmouth University, USA)

The spliceosome is a target for glycation in methylglyoxal-induced apoptosis and is shielded by glyoxalase 1 in multidrug resistance-linked cancer chemotherapy

Dr Muhanad Alhujaily
(Bisha University, Kingdom of Saudi Arabia)

Methylglyoxal targets proteins involved in mitotic fidelity

Leigh Donnellan
(University of South Australia, Australia)

Virtual Trade Exhibition (Exhibitors available on-line for inquiries and discussion)

Design and synthesis of near-infrared fluorescent probe targeting tumour metabolite methylglyoxal for visualization study

Prof Chunyong Ding
(Shanghai Jiaotong University, China)

Glycation and machine learning – diagnostic algorithms for diabetes, arthritis and autism

Prof Naila Rabbani
(Qatar University, Qatar)

Glycation based therapeutics: Glo1 inducers and Glo1 inhibitors. COVID-19 repurposing

Prof Paul J Thornalley
(QBRI/HBKU, Qatar)

Measurement of glyoxalase activities

Dr Sowndramalingam Sankaralingam
(Qatar University, Qatar)

Genetics of glycation – glycated hemoglobin, GLO1 single nucleotide polymorphisms and copy number variation

Maryam Al-Motawa
(QBRI/HBKU, Qatar)

Assay of glyoxalase metabolites: methylglyoxal, S-D-lactoylglutathione and D-lactate

Prof Paul J Thornalley (QBRI/HBKU, Qatar)

Quantitation of glycation adducts by stable isotopic dilution analysis LC-MS/MS

Prof Naila Rabbani
(Qatar University, Qatar)

Proteomics of glycation

Dr Patrick Wijten
(QBRI/HBKU, Qatar)

Application of functional genomics in studies of dicarbonyl stress

Dr Mingzhan Xue
(QBRI/HBKU, Qatar)

Mathematical modelling of glycation

Dr Alberto da la Fuente (QBRI/HBKU, Qatar)

Glycation in drug repurposing for COVID-19

Dr Hebah Al Khatib
(Qatar University, Qatar)

Inducible pluripotent stem cells (iPSC) application in diabetes and glycation research

Dr Essam Abdelalim
(QBRI/HBKU, Qatar)

• Grand challenges in glycation research – Doha Glycation Declaration 2021
• IMARS Society – change of President

Prof Paul J Thornalley
(IMARS President, QBRI/HBKU, Qatar)